A vaccine against the Coronavirus (SARS-CoV 2), experts say, in a few months. To be able to, the efficiency of the estimate, need to know the virologist, but, among other things, how quickly the pathogen is changing. He would mutate rapidly, would be a vaccine soon is ineffective. In the case of the flu pathogen that is the case, therefore, the pharmaceutical companies need to develop each year new sera directed against the current strains of the Virus.
there is good news: Apparently SARS-CoV-2, the lung disease Covid-triggers 19 mutates, very slowly. The researchers found the bioinformaticians Niema Moshiri from the University of California in San Diego. They had investigated the evolutionary tree of the pathogen. This concept is based on the theory of evolution of Charles Darwin and describes how the genome of an organism has changed over time and, thus, also its properties change. < / h3> Reported corona virus cases in Germany (click on your state)
Moshiri and his colleagues wanted to learn more about how the genes of the Virus to work. The goal was to see how quickly it can spread, but also what type of vaccine would be particularly effective. “For scientists, such as health authorities, it would be helpful to be able to the spread of track,” writes Moshiri on the Internet portal “LiveScience”. “We discovered, however, that SARS-CoV-2 is mutated, apparently, slower than the causative agents of seasonal flu.” This was for the development of a vaccine is very important.
researchers studied the genome of the Virus
In their analyses, the researchers took the genetic material of the pathogen under the microscope, which consists of a so-called ribonucleic acid (RNA). This, in turn, is built from four Nucleotides, whose sequence, structure and function of the cells produced the proteins determined. This sequence changes due to mutations, the properties of the proteins change. Viruses can become more or less infectious, or they can infect other organs, or even new organisms.
Today’s sequencing machines allow to determine the sequence of nucleotides, and thus the structure of the RNA in a short period of time. With this technique, Moshiri was able to characterize the genetic makeup (genome) of SARS-CoV-2. He then determined on the basis of model calculations of the evolutionary history of the Virus. As a result, what is the structure of the genome has had in the past, and the time in which its present configuration is reached, which in turn allows an estimation of the mutation rate. #Corona care: Germany helps – FOCUS Online
- On our interactive map of Germany showing which organizations in your area offer help.
- We cooperate with Germany’s largest social network for neighbors: nebenan.de. Here, everyone can offer help or a form to ask for help – for yourself or about the grandma.
- In our #corona care-Facebook-group have formed a network of more than 11,000 people. You post offers of help or requests.
- Under the E-Mail address deutschland-hilft-sich@focus.de help seekers get personal advice.
- anyone Who wants to hang slips of paper with the request for help or offers of help, will find templates to Download.
- We are looking for the stories that make, now, courage! Of small, brilliant ideas and people with big heart.
- We organize actions against the Corona-Koller: fitness coach Detlef D! Soost presented each day, a Workout, editors read them exciting stories …
The result: In the case of SARS-CoV-2, there are less than 25 mutations per year. Flu viruses, however, have a 50 mutations per year, double the Rate. “Because the genome of SARS-CoV-2 is almost twice as large as that of the flu virus to mutate, this is actually about four times faster than the excitation of Covid-19,” says Moshiri. “This is exactly what allows you to escape the vaccines again and again.” The significantly slower mutation rate of SARS-CoV-2 let’s now hope that the development of a permanently effective vaccination is successful.
In addition, you could also use this method to detect which genes the mutations occur, Moshiri more. Also this is for the vaccine development is important. At the same time, will clearly show whether there are in a city of several separate outbreaks caused by different virus strains.
- reading tip: All of the developments to the outbreak of the Coronavirus you read in the News Ticker
map of hope shows, who is doing what
in the Meantime, researchers from all over the world carry their data on the Central Internet platforms. One of them is the “next train”, which contains in many languages information about Covid-19, influenza, Ebola and other infectious diseases. Researchers, but also the General Public can access it in real-time.
What research activities are global to the Coronavirus, and Covid-19, shows an Online map, the GIS experts at the University of Heidelberg, together with the doctors of the local University hospital have developed. This “map of hope” is based on data from the world health organization and shows who is researching where what. “Scientists and physicians around the world have responded to the outbreak of the Corona-pandemic immediately with targeted research activities,” explains Geoinformatics Professor Alexander Zipf, one of the authors of the map.
“In contrast to various cards, the case numbers and the spread of the Virus, represent, combine, and visualize spatial data and information on clinical studies and scientific publications.”
The user can use the card, where clinical trials are conducted, be it in the diagnosis, to understanding of Disease and methods of treatment or in the area of advanced therapy medicinal products and vaccines. In addition, studies are covered, for instance, investigating how the pandemic affects the Helping. The places to city-level accurate. The map is freely available on the Internet. To facilitate the public’s flow of information and contacts between the scientists allow.
More about Corona:
- so Far, the assumption applied in the corona of a crisis as a General medical consensus that you’ve built as Covid-19-Patient has survived the disease for a certain period of time immunity. A recent study from South Korea, however, brings new insights. In a series of tests, the Virus has been reactivated in some people and again demonstrated.
- For weeks, the schools in Germany are tight, parents need to supervise their children themselves. Officially, the lessons will start after the Easter holidays. But how and exactly when, no one knows at the moment. The research Foundation of the Leopoldina is now a cause for hope.
Germany’s bewegendster Corona Song: “Victoriam” – Listen, we support the good cause
We do not leave anyone alone. With the Song “Victoriam” supports the action of #corona care boards in Germany.
Now “Victoriam” to listen to
See you in FOCUS Online/Wochit you will See in the
