Sergei Sobyanin announced the implementation of the programme of studies of population immunity — mass screening of Muscovites for the presence of antibodies to the new coronavirus infection. The decision was made at the end of the videoconference with the medical members of the clinical Committee for combating coronavirus.
He said that now it is possible to quickly and efficiently identify people who contracted coronavirus, as well as those who have chickenpox and has immunity. The new system will allow every few days conduct constant screening tests, to determine the number of patients or survivors coronavirus Muscovites, to carry out timely diagnosis and treatment of these people, and also will help to identify the actual number of people in Moscow that somehow collided with the coronavirus.
the Tests will be carried out using the ELISA-method (enzyme immunoassay). It can detect the presence or absence in the blood of the patient IgM antibodies (a marker for the presence of coronavirus infection) and IgG (a marker of immunity to COVID-19).
According to him, the new testing system will also apply to enterprises, especially those where employees have frequent contacts with citizens. We are talking about medical institutions, municipal services, law enforcement, public transport.
Mass screening will help to identify the coronavirus primarily those who have the disease in asymptomatic form. And he will give relevant information about the formation of population immunity (the proportion of the population have developed immunity). This will help to predict the future course of the pandemic and to make informed decisions on the abolition or preservation of existing restrictions.
According to the Mayor, this system will help to make combating coronavirus more effective. Data screening will permit early treatment of patients to determine the tactics of the medical system of the city, as well as adjust measures to combat the spread of coronavirus. “This is necessary in order to adequately make decisions related to restrictive measures, work of the enterprises of the sphere industry, construction, science, trade, services and so on, so that we know where we’re going, what stage of complexity are promptly and adequately take the necessary measures”, — said Sergey Sobyanin.
the Head of the Department of laboratory diagnostics, research Institute named after N. In. Sklifosovsky Michael short Years noted that the new system let�� to see the real picture of the spread of coronavirus infection. In his opinion, the laboratory system can be used after the end of the pandemic.
In the opinion of the Director, National research centre of epidemiology and Microbiology named after N. F. Gamalei Alexander Ginzburg, determination of the degree of population immunity, especially in dynamics, for several days, from week to week, gives a pilot the opportunity to predict the further development and the process of the disease.
In turn, the Deputy Director on scientific work of the National research centre of epidemiology and Microbiology named after N. F. Gamalei Denis Logunov said that the center for the study received 1961 plasma specimen. They were examined for the presence of a sufficient number of antibodies.
Chief freelance specialist on diagnostics and treatment of HIV infection of the Department of health of Moscow Alexey Mazus believes that to effectively combat the coronavirus it is necessary to increase the number of tests. As an example, he cited the mass screening for HIV infection, which helps to prevent the growing number of cases and reduce the spread of infection.
“there are a lot similar in the sense that more than 80 percent of people who encountered with this virus have no symptoms or suffer only very mild form. Accordingly, they do not know anything about the disease. And here is just the same model — identification of people is by serological diagnosis, because it only gives the opportunity of screening mass and identify people, which can be contagious and are a threat to others,” said Alexei Mazus.
According to him, the spread of coronavirus infection can also be the impetus for the creation of a universal vaccine against different viruses. “Vector vaccine, which was developed in Moscow, the most suitable for the creation of such multivoltine, — said Alexei Mazus. — Know about the trials that are about to begin. They need to be successful from the experts all of this is.”
the Experts agree that people who are sick with the virus without clinical manifestations, are the main source of infection. ELISA method will contribute to early isolation of cases and overall reduction in the number of patients with severe form of the disease.
Sergei Sobyanin stressed that any weakening of the regime of self-isolation leads to an increase in the number ambulance calls, hospitalizations. In the face of a possible epidemic, he said, will have to live more than one or two months.
“We quickly yourself this situation can not go, we have there is a risk of resumption of transmission until until we get effective vaccine or will not happen something wonderful, what we’re not talking. This means that we live and will live in a new reality and the weakening of the mode the isolation should not affect the spread of the coronavirus. Why? Because we need to provide this attenuation mode of self-isolation, which would have led to the spread of the virus,” said the Mayor.
Enterprise starting a job should ensure that their territory was created by such a regime that would minimize the risks of infection, and citizens need to instill a new — responsible — behavior.
“Our citizens should instill for ourselves and for others new responsible standards of behavior that would best protect them and their loved ones from contact spread of the coronavirus,” — said Sergey Sobyanin.
According to him, the whole health system need to continue to keep in combat mode. Health care institutions should at any time be ready to provide all necessary medical assistance.
Clinical Committee COVID-19 — this is temporary collegial body established on the initiative of Moscow doctors for the period of counter new coronavirus infection. Its main objectives is to systematize scientific and practical information about treating patients with the coronavirus, generate recommendations and algorithms of medical care for urban health facilities, as well as choose optimal technology of prevention, diagnosis, treatment and rehabilitation of patients who test positive for coronavirus.
as part of the clinical Committee of 25 specialists. Among them are representatives of the largest urban health facilities where they treat patients with coronavirus infection: the Director of the research Institute of emergency care named after N. In. Sklifosovsky Sergei Petrikov, the chief physician of city clinical hospital n 40 in Kommunarka Denis Protsenko, chief doctor of city clinical hospital n 52 Maryana Lysenko, the chief physician of Station of ambulance and emergency care name A. C. Puchkova Nikolai plavunov and other. The Committee is comprised of the main extraordinary specialists of the Department of health of the city of Moscow in the disciplines that are directly related to the diagnosis and treatment of patients with coronavirus infection. Among them, the chief freelance specialist pulmonologist Andrey belevskiy, chief freelance specialist — clinical pharmacologist Marina Zhuravleva, chief expert in radiation and instrumental diagnostics Sergey Morozov and others.
Chairman of the clinical Committee, the Minister of Moscow Government, head of the healthcare Department Alexey Khripun.
Thanks to the initiatives of the clinical Committee managed to form a new routing of patients, diagnosis and clinical decision-level admissions. So, if on arrival at hospital the patient has no test results for coronavirus, but when examined in the emergency Department revealed signs of the disease, the person hospitalitynet are as patient with COVID-19. This allows to speed up the provision of medical care.
Also in the scheme of diagnosis included CT-diagnosis. That is, the presence of negative smears on coronavirus in patients with signs of respiratory disease will not completely eliminate the novel coronavirus infection. The only reliable diagnostic study in this situation — computer tomography of lungs and its interpretation in combination with the clinical picture of the disease. The work includes power 42 municipal clinics and two hospitals — total 48 CT apparatus.
In the capital uniform system of hospitals, treating a coronavirus and pneumonia. In today’s conditions of pneumonia in almost all cases it is viral in nature.
9 and April 21 held a teleconference with medical experts from European countries, USA and China on issues COVID-19. On 14 April a meeting was held with the delegation of medical experts from China — the main extraordinary specialists of the healthcare Department of Moscow and chief physicians Metropolitan hospitals, discussed with Chinese colleagues the issues of prevention and treatment of infection.
Now is the preparation and approval methodical recommendations Department of health for the prevention, diagnosis and treatment of new coronavirus infection. Prepare proposals for inclusion into the provisional guidelines of the Ministry of health of Russia.
Today, under the observedclinical training Committee in cooperation with the National research centre of epidemiology and Microbiology named after N. F. Gamalei created a new diagnostic test system the expertise to detect genetic material of coronavirus (polymerase chain reaction). Also developed diagnostic panel, which will determine the sensitivity and specificity used in the laboratory network of test systems. Work on diagnostic systems for the analysis of the plasma of the patients, recovering from a new coronavirus infection in the presence of antibodies. Is testing several clinical test-systems for antibodies to SARS-CoV-2, as well as assessment of viral load in the background of the different treatment regimens of patients with COVID-19.
in Addition, create a diagnostic panel of complexes of cytokines. It will help to predict the course and the effectiveness of various methods of treatment of the most severe patients with COVID-19. To assess the effectiveness of new drugs are being developed three-dimensional culture of lung tissue. Also, doctors are studying the effectiveness of taking hydroxychloroquine for the prevention of coronavirus.
