Vladimir Putin announced the change agenda: the improvement of the situation with the coronavirus, he said, lets go back to the strategic objectives and large-scale projects, such as the development of genetic technologies. At the meeting, scientists described how their development helping to create unique preparations to treat glioblastoma Anastasia Zavorotnyuk and defend the gold medal biathlete Evgeny Ustyugov. However, without the coronavirus is also not done: it has created a genetics test kits and drugs from new infection, and in the fall promise to register the vaccine.
for nearly two months, the President almost on a daily basis engaged in coronavirus and neutralization of the effects of the pandemic on citizens and the economy. But it has now become possible to slightly let go of the reins. “Recovery is normal, the normal rhythm of life it is essential to ensure dynamic, efficient solution of strategic objectives and our large-scale projects with a long horizon,” he said. According to him, one of these priorities are genetic technologies. The state programme of development was adopted a little over a year ago, and during that time the country has managed to create three genomic center of the world level. It is expected that they will develop in various fields — from medicine and agriculture to industry and energy. “The scale of the task, and breakthrough value for the country program for the development of genetic technologies comparable with nuclear and space projects of the XX century”, — said Putin.
the Main technological partner of geneticists was the company “Rosneft”. Igor Sechin at the meeting expressed readiness to build a modern biotechnology campus and a full genetic screening of their employees. “The company employs over 350 thousand people, and obtaining primary genetic data for health and research work is of great importance”, — he stressed. According to Sechin, the method will “identify changes that have accumulated in the course of human life under the influence of aggressive environmental conditions,” and collected materials will be used to develop the most rational methods of treatment.
Other participants of the meeting confirmed the importance of genetic research to fight serious, sometimes incurable diseases. Oncolytic viruses that are being developed in the Institute of molecular biology. Engelhardt, according to its Director, Alexander Makarov, can kill breast cancer cells and brain. Tests are conducted on volunteers with IV end-stage, which conventional therapy is not helping. And there are “quite a large percentage of cases, when there is remission and patients nachinaut lead a normal lifestyle.” Particularly well, according to Makarov, it can be seen in the case of glioblastoma. “This malignant tumor often began to hit our leading artists, cultural figures, and, unfortunately, with a sad outcome. Remained until only Anastasia Zavorotnyuk, which is struggling with this disease, and we try to take part in it” — suddenly announced information that was not previously disclosed, Makarov. He said that relatives of the actress gave scientists her cancer cells, which were multiplied, and in College they already have picked up the viruses that kill the tumor. But while the situation at Zavorotnyuk not so anxious to apply the experimental technology, the scientist believes.
According to Makarov, the genetic studies will also allow us to protect the good name of the Russian biathlete Evgeny Ustyugov, which is due to the high content of hemoglobin in the blood accused of doping and stripped of an Olympic gold medal. Having studied the genetic material of the athlete and his / her family members, scientists have identified rare mutations, indicating that the increased level of hemoglobin Ustyugov observed constantly. “This is his unique feature,” — said Makarov, expressing hope that these surveys will be taken into consideration by the court of arbitration for Sport. Putin thanked the scientists: “This assistance more than ever”.
as for the coronavirus, without genetics would not have any of the test systems, no new drugs, no vaccine, which is already in a high stage of readiness. Alexander Makarov told Putin, how do you do a humanized mouse ordered by Rospotrebnadzor for testing vaccines and drugs from COVID-19. Animals, according to him, grafted feature of cells of the human lung — a receptor, to which clings the new coronavirus. But one mouse has introduced a special gene to study the cytokine storm — it often leads to severe course of illness and even death of patients. “This mouse managed to find effective blockers of cytokines”, — said the scientist. “Fantasy gives rise to a variety of images of these humanized mice, — shivered Putin. — I hope everything will be under control.” — “The mouse is already a monument — she sits and knits its genome — reassured Makarov. But in General, we have a wide range of rabbits, rats, fish and even worms.”
In the center of Virology of the mouse will be communicated in early June. In the same month, “Vector” intends to complete preclinical studies of possible prototypes of the vaccine, and in September, after a clinical trial of 300 volunteers, to register the finished product.
